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Bone Disorders & Blood Transfusion โ€” UPSC CMS MCQs (Medicine) · 9 questions

2021 P1 Q60

Q1. Use of which of the following drugs may result in osteoporosis? 1. Phenytoin 2. Lithium 3. Methotrexate 4. Azathioprine Select the correct answer using the code:

  1. 1, 2 and 3
  2. 1, 2 and 4
  3. 1, 3 and 4
  4. 2, 3 and 4

Answer & explanation โ€” reveal it in the interactive practice above.

PYQ 2020โ€“2025 โ€” page 87

2021 P1 Q84

Q2. First line drug treatment to reduce fractures in osteoporosis is:

  1. Bisphosphonates
  2. Denosumab
  3. Teriparatide
  4. Raloxifene

Answer & explanation โ€” reveal it in the interactive practice above.

PYQ 2020โ€“2025 โ€” page 94

2022 P1 Q46

Q3. Which one of the following is a subcutaneous preparation useful for the treatment of osteoporosis?

  1. Denosumab
  2. Alendronate
  3. Zoledronic acid
  4. Raloxifene

Answer & explanation โ€” reveal it in the interactive practice above.

PYQ 2020โ€“2025 โ€” page 153

2022 P1 Q47

Q4. Which of the following are correct with regard to osteoporosis? 1. It does not cause symptoms until a fracture occurs 2. Vertebral fracture can present with loss of height, in absence of pain 3. Smoking is protective 4. It sometimes presents incidentally as radiological osteopenia Select the correct answer using the code:

  1. 1, 2 and 3
  2. 1, 2 and 4
  3. 1, 3 and 4
  4. 2, 3 and 4

Answer & explanation โ€” reveal it in the interactive practice above.

PYQ 2020โ€“2025 โ€” page 153

2020 P1 Q50

Q5. Cryoprecipitate cannot be used for treatment of which one of the following conditions?

  1. Von Willebrand disease
  2. Hypofibrinogenemia
  3. Hemophilia B
  4. Hemophilia A

Answer & explanation โ€” reveal it in the interactive practice above.

PYQ 2020โ€“2025 โ€” page 20

2023 P1 Q32

Q6. With regard to transfusion therapy, cryoprecipitate is a rich source of which of the following? 1. Fibrinogen 2. Clotting factor VIII 3. Clotting factor IX 4. von Willebrand factor Select the correct answer using the code:

  1. 1, 2 and 3
  2. 1, 2 and 4
  3. 1, 3 and 4
  4. 2, 3 and 4

Answer & explanation โ€” reveal it in the interactive practice above.

PYQ 2020โ€“2025 โ€” page 215

2020 P2 Q32

Q7. Which one of the following is NOT a complication of massive blood transfusion?

  1. Coagulopathy
  2. Hypocalcemia
  3. Hyperthermia
  4. Hyperkalemia

Answer & explanation โ€” reveal it in the interactive practice above.

PYQ 2020โ€“2025 โ€” page 46

2022 P1 Q35

Q8. Which one of the following is correct regarding blood components in clinical practice?

  1. ABO blood group antigens are polypeptide chains on the surface of RBCs
  2. Platelets can be stored for up to 35 days
  3. Hemolytic disease of the newborn occurs when motherโ€™s IgA anti-RBC antibodies cross the placenta and lyse fetal RBCs
  4. Transfusion-associated GVHD can be prevented by prior irradiation of transfused blood

Answer & explanation โ€” reveal it in the interactive practice above.

PYQ 2020โ€“2025 โ€” page 150

2023 P1 Q33

Q9. Which of the following viruses can be transmitted via transfusion of infected blood? 1. Hepatitis B virus 2. Hepatitis C virus 3. Human immunodeficiency virus 4. Parvovirus B19 Select the correct answer using the code:

  1. 1 and 3 only
  2. 2 and 4 only
  3. 1, 2 and 3 only
  4. 1, 2, 3 and 4

Answer & explanation โ€” reveal it in the interactive practice above.

PYQ 2020โ€“2025 โ€” page 215

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