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Cardiovascular System (CVS) — UPSC CMS MCQs (Medicine) · 57 questions

2020 P1 Q4

Q1. All of the following are indications for treadmill testing / exercise-testing EXCEPT:

  1. To confirm the diagnosis of angina
  2. To evaluate stable angina
  3. To assess outcome after coronary revascularization
  4. To evaluate the treatment efficacy of antianginal drugs

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 8

2021 P1 Q1

Q2. A 60-year-old man comes to emergency with history of chest pain, which is acute onset. The ECG shows ST depression and T waves inversion. Cardiac biomarkers in blood are not elevated. What will be the appropriate management?

  1. Oxygen + Aspirin + Ticagrelor + Metoprolol
  2. Oxygen + Sublingual Nitroglycerin + Antiplatelets + Streptokinase
  3. Antiplatelets + LMW Heparin subcutaneous
  4. Oxygen + Sublingual Nitroglycerin + Digoxin

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 70

2021 P1 Q5

Q3. A 50-year-old man reports to Emergency with breathlessness, palpitations and acute chest pain. On auscultation, there is systolic murmur at apex and ECG shows ST elevations in anterior chest leads. Which one of the following would be the next choice of investigation?

  1. Cardiac marker troponin T/I
  2. Echocardiography
  3. TMT
  4. 24-hour Holter monitoring

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 72

2023 P1 Q68

Q4. A 60-year-old diabetic female presents with acute myocardial infarction. ECG changes include ST elevation greater than 1 mm in lead aVR. The likely localization of thrombosis is in

  1. Right Coronary Artery
  2. Distal LAD
  3. Left Circumflex Artery
  4. Left Main or Proximal LAD

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 225

2025 P1 Q2

Q5. Consider the following statements for diagnosing ventricular aneurysm in a patient with recent myocardial infarction: I. Paradoxical impulse on chest wall II. Persistent ST elevation on ECG III. Unusual bulge from cardiac silhouette on X-ray IV. Presence of pulsus paradoxus Select the correct answer using the code:

  1. I and II only
  2. I and IV
  3. I, II and III
  4. II, III and IV

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 366

2024 P1 Q2

Q6. The SA node is situated at the junction of:

  1. SVC and RA
  2. SVC and LA
  3. LA and LV
  4. IVC and RA

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 277

2024 P1 Q3

Q7. High output cardiac failure is caused by which of the following diseases? 1. Beri-Beri 2. Severe anaemia 3. Thyrotoxicosis Select the correct answer using the code:

  1. 1 and 2 only
  2. 2 and 3 only
  3. 1 and 3 only
  4. 1, 2 and 3

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 277

2022 P1 Q8

Q8. Left atrial dilatation on X-ray chest is characterized by which of the following? 1. Straight left heart border 2. Rounding of left heart border 3. Double cardiac shadow 4. Widening of the angle of carina Select the correct answer using the code:

  1. 1 and 3 only
  2. 1, 2 and 4
  3. 1, 3 and 4
  4. 2, 3 and 4

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 143

2023 P1 Q10

Q9. A 28-year male is suspected of having hypertrophic obstructive cardiomyopathy (HOCM). Which of the following statements are likely to be true on his examination? 1. Maneuvers that decrease LV preload will cause the murmur to intensify. 2. Maneuvers that decrease LV afterload will cause decrease in intensity of murmur. 3. Murmur of HOCM becomes softer with passive leg raising. 4. Murmur of HOCM becomes louder with squatting. Select the correct answer using the code:

  1. 1 and 3
  2. 2 and 3
  3. 2 and 4
  4. 1 and 4

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 209

2023 P1 Q1

Q10. Thickened ventricular wall with normal diastolic function is a feature of

  1. hypertrophic cardiomyopathy
  2. restrictive cardiomyopathy
  3. endomyocardial fibrosis
  4. athlete’s heart

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 208

2020 P1 Q3

Q11. A 40-year-old lady comes to outdoor clinic with complaints of sudden onset chest pain. The chest X-ray shows bilateral pneumothorax. Examination reveals long arms, legs and fingers (arachnodactyly), scoliosis, high arched palate, joint hypermobility, and a pansystolic murmur at cardiac apex. Which one of the following diseases is most likely?

  1. Takayasu’s arteritis
  2. Raynaud’s syndrome
  3. Marfan’s syndrome
  4. Rheumatic heart disease – Mitral regurgitation

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 8

2020 P1 Q5

Q12. Kussmaul’s sign is present in all of the following conditions, EXCEPT:

  1. Massive Pulmonary Embolism
  2. Restrictive Cardiomyopathy
  3. Hypertrophic Cardiomyopathy
  4. Right Ventricular Infarction

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 8

2022 P1 Q9

Q13. A 30-year-old male is being evaluated for shortness of breath. On examination of the jugular venous pulse (JVP), there is a rise in the JVP on inspiration. Which one of the following is the most likely diagnosis?

  1. Constrictive pericarditis
  2. Atrial septal defect
  3. Aortic regurgitation
  4. Severe mitral stenosis

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 143

2023 P1 Q3

Q14. A patient with peripheral edema has the following findings: a soft systolic murmur at the lower left sternal border with raised JVP showing prominent C-V wave. The murmur increases in intensity on deep inspiration. The most likely valvular abnormality is

  1. ventricular septal defect
  2. mitral regurgitation
  3. tricuspid regurgitation
  4. mitral valve prolapse

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 208

2023 P1 Q4

Q15. Kussmaul’s sign is a clinical feature of

  1. Constrictive pericarditis
  2. Hypertrophic obstructive cardiomyopathy
  3. Anteroseptal myocardial infarction
  4. Dilated cardiomyopathy

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 208

2024 P1 Q1

Q16. The height of the Jugular Venous Pulse is determined by:

  1. Right atrial pressure
  2. Right ventricle pressure
  3. Left atrial pressure
  4. Left ventricle pressure

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 276

2022 P1 Q10

Q17. A 24-year-old man presents with acute onset shortness of breath with precordial chest pain. ECG reveals ST elevation with upward concavity and PR segment depression in lead V2 to V6 and reciprocal changes in lead aVR. The most likely diagnosis is:

  1. Anterior wall myocardial infarction
  2. Acute pericarditis
  3. Anterior wall aneurysm
  4. Aortic dissection

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 144

2023 P1 Q71

Q18. Which of the following are typical physical findings in pericardial effusion? 1. Raised JVP 2. Hypotension 3. Oliguria 4. Water hammer pulse Select the correct answer using the code:

  1. 1, 2 and 3
  2. 1, 2 and 4
  3. 1, 3 and 4
  4. 2, 3 and 4

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 226

2022 P1 Q6

Q19. Which of the following produce loud S1 on cardiac auscultation? 1. Anemia 2. Pregnancy 3. Thyrotoxicosis 4. Mitral regurgitation Select the correct answer using the code:

  1. 1, 2 and 3
  2. 1, 2 and 4
  3. 1, 3 and 4
  4. 2 and 3 only

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 143

2023 P1 Q2

Q20. In which of the following cases does paradoxical splitting occur? 1. Severe aortic stenosis 2. Right bundle branch block 3. Right ventricular pacing 4. Hypertrophic obstructive cardiomyopathy Select the correct answer using the code:

  1. 1, 2 and 3
  2. 1, 2 and 4
  3. 1, 3 and 4
  4. 2, 3 and 4

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 208

2024 P1 Q4

Q21. Reverse splitting of second heart sound is most commonly seen in:

  1. ASD
  2. Severe MR
  3. LBBB
  4. Pulmonary hypertension

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 277

2025 P1 Q1

Q22. Which of the following heart sounds are best heard with the bell of stethoscope? I. Opening snap II. Systolic click III. Third heart sound IV. Mid diastolic murmur Select the correct answer using the code:

  1. I and IV
  2. II and III only
  3. III and IV
  4. I, II and III

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 366

2023 P1 Q72

Q23. Which of the following conditions can produce a third heart sound (S3) on auscultation? 1. Young age 2. Pregnancy 3. Left ventricular failure 4. Mitral stenosis Select the correct answer using the code:

  1. 1, 2 and 3
  2. 1, 2 and 4
  3. 1, 3 and 4
  4. 2, 3 and 4

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 226

2021 P1 Q9

Q24. Which one of the following statements is correct regarding Opening Snap in cardiac auscultation?

  1. It is a high pitched diastolic sound
  2. It is due to opening of stenosed aortic valve
  3. It indicates pulmonary arterial hypertension
  4. It precedes the aortic component of second heart sound

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 73

2025 P1 Q5

Q25. Which of the following statements is correct regarding the Opening Snap (OS) in a patient of mitral stenosis?

  1. OS is best heard with the bell of stethoscope
  2. Intensity of OS becomes louder when the valve is calcified
  3. OS moves closer to the second sound (S2) as the stenosis becomes more severe
  4. OS is best heard at the second left intercostal space

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 369

2023 P1 Q5

Q26. A patient has a cardiac murmur that is best heard at the right second intercostal space. It increases with expiration. Also, the murmur reduces in intensity during sustained handgrip but increases in intensity on inhalation of amyl nitrite. The likely lesion is

  1. ventricular septal defect
  2. aortic stenosis
  3. hypertrophic obstructive cardiomyopathy
  4. mitral regurgitation

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 208

2024 P1 Q6

Q27. A 70-year-old man with dyspnoea on exertion has been found to have a single second heart sound and a loud diamond-shaped, rough quality systolic murmur best heard at the right 2nd intercostal space, radiating to the right carotid artery. Which one of the following is the likely diagnosis?

  1. Patent ductus arteriosus
  2. Ventricular septal defect
  3. Aortic stenosis
  4. Pulmonary stenosis

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 278

2025 P1 Q4

Q28. Which one of the following is correct with regard to Carey Coombs murmur?

  1. Soft systolic murmur due to mitral regurgitation
  2. Soft mid-diastolic murmur due to mitral valvulitis
  3. Harsh early diastolic murmur due to aortic regurgitation
  4. Blowing late systolic murmur due to aortic stenosis

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 368

2025 P1 Q79

Q29. The murmur of mitral regurgitation is best heard at

  1. Tricuspid area
  2. Aortic area
  3. Cardiac apex
  4. Pulmonary area

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 399

2023 P1 Q6

Q30. In the modified Duke criteria for infective endocarditis, which one of the following is not a major criterion?

  1. New partial dehiscence of prosthetic valve
  2. Positive blood culture
  3. Roth’s spots
  4. New valvular regurgitation

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 209

2023 P1 Q12

Q31. Which one of the following is a manifestation of vascular phenomenon in modified Duke criteria?

  1. Osler’s node
  2. Roth’s spots
  3. Janeway’s lesions
  4. Glomerulonephritis

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 210

2021 P1 Q90

Q32. Cardiac outflow tract defect, thymic hypoplasia, cleft palate and hypocalcemia are clinical features of which gene disorder?

  1. Angelman syndrome
  2. Williams syndrome
  3. Smith-Magenis syndrome
  4. DiGeorge syndrome

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 96

2020 P1 Q7

Q33. In an ECG recording, P wave is produced by:

  1. Atrial depolarisation
  2. Atrial repolarisation
  3. Ventricular depolarisation
  4. Ventricular repolarisation

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 9

2021 P1 Q3

Q34. Which one of the following is not a differential diagnosis of ST segment elevation in ECG?

  1. Acute pericarditis
  2. Trauma to ventricles
  3. Hypothermia
  4. Hypocalcemia

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 72

2023 P1 Q8

Q35. Osborn waves in ECG show prolonged repolarization with a distinctive convex elevation of the ‘J’ point. These waves are associated with

  1. systemic hypothermia
  2. acute pericarditis
  3. acute myocarditis
  4. Brugada syndrome

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 209

2023 P1 Q73

Q36. Which of the following statements are true about the PR interval? 1. It denotes atrial depolarization. 2. Normal duration is 0.12 seconds to 0.20 seconds. 3. Prolongation denotes impaired AV nodal conduction. 4. A short PR interval occurs in WPW syndrome. Select the correct answer using the code:

  1. 1, 2 and 3
  2. 1, 2 and 4
  3. 1, 3 and 4
  4. 2, 3 and 4

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 226

2020 P1 Q1

Q37. A chronic alcoholic develops a paroxysm of palpitations after alcohol binge. Which of the following arrhythmias is most likely?

  1. Ventricular fibrillation
  2. Ventricular premature complex
  3. Atrial flutter
  4. Atrial fibrillation

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 8

2020 P1 Q6

Q38. Which one of the following is NOT a common cause of atrial fibrillation?

  1. Mitral regurgitation
  2. Hypothyroidism
  3. Hypertension
  4. Acute myocardial infarction

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 8

2020 P1 Q8

Q39. Which one of the following modalities is NOT used in the treatment of ventricular tachycardia?

  1. DC Cardioversion
  2. Injection Lignocaine
  3. Injection Amiodarone
  4. Injection Adenosine

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 9

2021 P1 Q4

Q40. Which one of the following is a non-shockable rhythm in respect to use of AED (Automatic External Defibrillator)?

  1. Monomorphic ventricular tachycardia
  2. Polymorphic ventricular tachycardia
  3. Ventricular fibrillation
  4. Pulseless electrical activity

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 72

2021 P1 Q8

Q41. A 35-year-old patient presents in the Emergency with sudden onset palpitations. His heart rate is 150/minute and gets reverted after carotid massage. The most probable diagnosis is:

  1. Paroxysmal supraventricular tachycardia
  2. Ventricular tachycardia
  3. Ventricular fibrillation
  4. Atrial flutter with block

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 73

2021 P1 Q6

Q42. Which of the following electro-cardiographic findings are manifestations of digitalis intoxication? 1. Ventricular bigeminy 2. Ventricular tachycardia 3. Atrial flutter 4. Atrial tachycardia with variable block Select the correct answer using the code:

  1. 1, 2 and 3
  2. 1, 2 and 4
  3. 1, 3 and 4
  4. 2, 3 and 4

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 72

2025 P1 Q6

Q43. Which one of the following responses to intravenous adenosine is correctly matched?

  1. Atrial fibrillation – Termination
  2. Atrio-ventricular nodal reentrant tachycardia – Termination
  3. Ventricular tachycardia – Termination and complete recovery
  4. Atrial flutter – Termination and complete recovery

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 369

2022 P1 Q2

Q44. A patient with ischemic heart disease on regular follow-up has a resting heart rate of 90 beats/minute. The patient is taking metoprolol 50 mg twice a day. Which one of the following drugs may be added to his prescription if he also has signs of heart failure?

  1. Ranolazine
  2. Diclofenac
  3. Prednisolone
  4. Ivabradine

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 142

2020 P1 Q2

Q45. Elderly man with history of Diabetes mellitus and coronary artery disease comes for follow-up, with complaints of muscle pains. Which one of the following drugs could be the most likely cause?

  1. Aspirin
  2. Glimepiride
  3. Enalapril
  4. Atorvastatin

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 8

2022 P1 Q1

Q46. A 52-year-old man with a history of coronary artery disease is on sublingual nitroglycerin SOS, metoprolol, aspirin and enalapril for the last year. He now complains of breathlessness and wheeze. Which one of the following drugs is most likely to be implicated for this new symptom?

  1. Enalapril
  2. Metoprolol
  3. Nitroglycerin
  4. Aspirin

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 141

2021 P1 Q11

Q47. A patient with Atrial Fibrillation on regular treatment presents with photosensitivity, skin discoloration and peripheral neuropathy. Which drug may be implicated?

  1. Digoxin
  2. Disopyramide
  3. Amiodarone
  4. Bisoprolol

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 74

2022 P1 Q7

Q48. Which of the following are correct about Ivabradine? 1. It may be of use in severe heart failure 2. It acts on SA node 3. It reduces heart rate 4. It is effective in atrial fibrillation Select the correct answer using the code:

  1. 1, 2 and 3
  2. 1, 2 and 4
  3. 1, 3 and 4
  4. 2 and 3 only

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 143

2022 P1 Q5

Q49. Which of the following drugs may be associated with leg swelling? 1. Calcium channel blockers 2. NSAIDs 3. Glucocorticoids 4. Mineralocorticoids Select the correct answer using the code:

  1. 1 and 2 only
  2. 2, 3 and 4 only
  3. 3 and 4 only
  4. 1, 2, 3 and 4

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 143

2020 P1 Q9

Q50. Which one of the following drugs is a Direct Renin Inhibitor?

  1. Benedipine
  2. Azilsartan
  3. Aliskiren
  4. Lisinopril

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 9

2020 P1 Q10

Q51. All of the following are causes of systolic hypertension with wide pulse pressure EXCEPT:

  1. Aortic regurgitation
  2. Thyrotoxicosis
  3. Patent ductus arteriosus
  4. Aortic stenosis

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 9

2020 P2 Q82

Q52. Which of the following measures can help reduce the risk of systemic hypertension? 1. Reduction in dietary intake of common salt 2. Controlling weight for age 3. Increasing potassium rich foods in the diet Select the correct answer using the code:

  1. 1 and 2 only
  2. 2 and 3 only
  3. 1 and 3 only
  4. 1, 2 and 3

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 59

2020 P2 Q114

Q53. DASH diet plan is advocated in the control of which one of the following diseases?

  1. Cancer
  2. Chronic Obstructive Pulmonary Disease
  3. Hypertension
  4. Rheumatic heart disease

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 66

2021 P2 Q105

Q54. The “DASH diet” is a lifestyle modification for management of which of these conditions?

  1. Cancer
  2. Diabetes
  3. Anemia
  4. Hypertension

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 136

2024 P1 Q99

Q55. In case of hypertensive emergency in a child, blood pressure should be reduced by up to:

  1. 10% over the first 8 hours
  2. 15% over the first 8 hours
  3. 10% in the first hour
  4. 15% in the first hour

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 310

2021 P2 Q104

Q56. Insulin Resistance Syndrome (Syndrome X) is associated with which of the following? 1. Type 2 Diabetes Mellitus 2. Hyperinsulinemia 3. Dyslipidemia 4. Hypercalcemia Select the correct answer using the code:

  1. 1, 2 and 3
  2. 1, 2 and 4
  3. 1, 3 and 4
  4. 2, 3 and 4

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 136

2022 P1 Q3

Q57. An 18-year-old boy got frostbite on his left foot after working in a snowy field for 5–6 hours. He complained of pain, numbness, and limited movement of his toes. The skin appeared white and waxy. Which one of the following is contraindicated as initial treatment?

  1. Rewarming by immersion of feet in a water bath at 40–44°C
  2. Massage
  3. Cleaning of the injured area with soap
  4. Use of analgesia and sterile dressing

Answer & explanation — reveal it in the interactive practice above.

PYQ 2020–2025 — page 142

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