2020 P1 Q30
Q1. Eradication of helicobacter pylori infection may prove beneficial in the following extra- gastric disorders EXCEPT:
- Unexplained vitamin B12 deficiency
- Idiopathic thrombocytopenic purpura
- Iron deficiency anaemia without gastro-intestinal bleeding
- Acute glomerulonephritis
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 14
2020 P2 Q12
Q2. All of the following are sequelae of peptic ulcer surgery EXCEPT:
- Bilious vomiting
- Dumping syndrome
- Diarrhea
- Increased appetite
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 42
2020 P2 Q18
Q3. Valentino’s syndrome is:
- Pain on per-vaginal examination in pelvic abscess
- Pain over the left shoulder in left hypochondriac collection
- Pain over the left groin in perirenal collection
- Pain in the right iliac fossa in perforated peptic ulcer
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 43
2021 P1 Q27
Q4. Consider the following statements in respect of Helicobacter Pylori:
1. It is a gram positive, spiral-shaped bacterium.
2. It uses an adhesion molecule (BabA) to bind to the ‘Lewis b’ antigen on gastric epithelial cells.
3. It produces ‘urease’ enzyme that helps to raise the pH around the bacterium.
4. It exclusively colonizes only ‘gastric-type’ epithelium.
Which of the above statements are correct?
- 1, 2 and 3
- 1, 2 and 4
- 2, 3 and 4
- 1, 3 and 4
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 78
2021 P1 Q28
Q5. The quadruple therapy regime (or OBMT regime) for Helicobacter Pylori eradication comprises which of the following drugs?
- Omeprazole, Bismuth sub citrate, Metronidazole, Tetracycline
- Ofloxacin, Bismuth sub citrate, Metronidazole, Tetracycline
- Omeprazole, Beclomethasone, Metronidazole, Tacrolimus
- Omeprazole, Beclomethasone, Mometasone, Tetracycline
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 78
2022 P1 Q20
Q6. Which of the following drugs are implicated in peptic ulcer disease, not caused by Helicobacter pylori and NSAIDs?.
1.Clopidogrel
2.Glucocorticoids
3.Bisphosphonates
4.Colloidal bismuth subcitrate
Select the correct answer using the code below:
- 1, 2, and 3
- 1 and 2 only
- 1, 3, and 4
- 2 & 4
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 146
2022 P2 Q29
Q7. Which of the following statements regarding peptic ulcers are correct?
1. Duodenal ulcers are more common as compared to gastric ulcers.
2. Helicobacter pylori and NSAIDs are most common causative agents.
3. Bleeding is the most common complication associated with posterior duodenal ulcer.
Select the correct answer using the code:
- 1 and 2 only
- 2 and 3 only
- 1 and 3 only
- 1, 2 and 3
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 182
2023 P1 Q30
Q8. Helicobacter pylori infection is associated with the development of which one of the following lymphoid malignancies?
- Burkitt’s lymphoma
- Hodgkin’s lymphoma
- Mucosa-associated lymphoid tissue lymphoma
- Adult T-cell leukemia/lymphoma
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 214
2023 P1 Q93
Q9. Which one of the following statements is correct with regard to peptic ulcer prophylaxis?
- Stress ulceration during clinical illness is uncommon
- Ulcer prophylaxis should be continued once absorption of enteral feed is established
- Proton-pump inhibitors (PPIs) are effective at reducing the incidence of ulceration
- PPIs when used with antibiotics may decrease the risk of Clostridium difficile infection
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 232
2023 P2 Q25
Q10. A young 28-year-old male was operated for duodenal ulcer perforation peritonitis. After recovering well for five days, he developed high fever with chills and symptoms of toxemia. He also experienced right shoulder tip pain and intractable hiccups. The most likely diagnosis is:
- Surgical site infection
- Postoperative peritonitis
- Subphrenic abscess
- Right lobe liver abscess
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 248
2024 P1 Q17
Q11. With regard to Helicobacter pylori eradication in peptic ulcer disease, consider the following statements:
1. Proton-pump inhibitor is taken with two antibiotics.
2. Treatment is prescribed for at least 7 days.
3. Treatment of Helicobacter pylori infection leads to vitamin B12 deficiency.
4. Patients requiring long-term NSAIDs should undergo Helicobacter pylori eradication therapy to reduce ulcer risk. Which of the statements are correct?
- 1, 2 and 3
- 1, 2 and 4
- 1, 3 and 4
- 2, 3 and 4
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 283
2024 P1 Q19
Q12. Which one of the following statements is correct regarding Upper Gastro Intestinal Bleeding (UGIB) ?
- Esophageal varices are the most common cause
- Eradication of Helicobacter pylori in patients with bleeding ulcers decreases the rebleeding rates to less than 5%
- Patients with cardiovascular disease who are on aspirin for secondary prevention should not restart their aspirin
- Trans jugular Intrahepatic Portosystemic Shunt (TIPS) should be considered as therapy only after one week of hospitalization for acute variceal bleeding
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 285
