2024 P1 Q11
Q1. Consider the following statements regarding Lofgren syndrome:
1. It is an acute illness and is more commonly seen in females.
2. It is a clinically distinct phenotype of sarcoidosis characterized by peripheral arthropathy and uveitis.
3. Clinical features include fever, erythema nodosum and bilateral lymphadenopathy.
Select the correct answer using the code:
- 1 and 2 only
- 2 and 3 only
- 1 and 3 only
- 1, 2 and 3
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 280
2023 P1 Q7
Q2. Which one of the following diseases affects predominantly large arteries?
- Granulomatosis with polyangiitis
- Polyarteritis nodosa
- Giant cell arteritis
- Eosinophilic granulomatosis with polyangiitis
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 209
2024 P1 Q41
Q3. A 75-year-old man presented with temporal headache, jaw pain, exacerbated by chewing and talking. Which one of the following investigations will most likely help in diagnosis?
- Temporal artery biopsy
- Electromyography
- MRI of the brain
- Carotid colour Doppler
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 291
2021 P1 Q83
Q4. Polyarteritis nodosa has peak incidence between the ages of:
- 10–20 years
- 20–30 years
- 30–40 years
- 40–50 years
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 94
2025 P1 Q60
Q5. A 42-year-old man presented with recurrent oral ulcers since one year, episodes of redness of eye and genital ulcers. Which one of the following tests is of diagnostic value?
- Mantoux test
- Drug-sensitivity test
- Pathergy test
- Patch test
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 392
2020 P2 Q74
Q6. The initial prevention strategy for antiphospholipid syndrome will be:
1. Steroids
2. Heparin
3. Low dose aspirin
4. Progesterone support
Select the correct answer using the code:
- 2 and 3
- 3 and 4
- 3 only
- 1 and 4
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 57
2022 P1 Q50
Q7. Which of the following can be used to monitor disease activity in rheumatoid arthritis?
1. Pain (visual analogue scale)
2. X-Ray of hands and wrists
3. DAS 28 score
4. ESR
Select the correct answer using the code:
- 1, 2 and 3
- 1, 2 and 4
- 1, 3 and 4
- 2, 3 and 4
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 154
2024 P1 Q82
Q8. Which one of the following antibodies is commonly associated with Drug-induced Lupus?
- Anti-centromere antibody
- Anti-Jo-1 antibody
- Anti-histone antibody
- Anti-RNP antibody
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 304
2025 P1 Q16
Q9. Which one of the following statements is correct in respect of pulmonary involvement in rheumatoid disease?
- Rheumatoid pulmonary nodules are usually asymptomatic and detected incidentally on imaging.
- Rheumatoid pulmonary nodules are often solitary and located near hilum.
- Pleural effusion in these patients is transudative and usually bilateral.
- Combination of pleural effusion and pneumoconiosis in these patients is known as Caplan syndrome.
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 375
2025 P2 Q45
Q10. The best drug for maintenance therapy of Systemic Lupus Erythematosus (SLE) during pregnancy is:
- Hydroxychloroquine
- Sulfasalazine
- Tacrolimus
- Progestins
Answer & explanation — reveal it in the interactive practice above.
PYQ 2020–2025 — page 437
